Coronavirus: Part 1 (ft. Ellie Duckworth)

This is it. Our biggest and most ambitious episode so far. In this massive multi-part special episode, we talk all things coronavirus. Matt and Kate are joined by Ellie Duckworth: A Master of Public Health graduate, specialising in epidemiology and biostatistics. In our opening episode, we try to give a bit of background and context to the current situation. We give a brief history of other coronavirus outbreaks, like SARS and MERS, which have given scientists a head-start when it comes to understanding this novel coronavirus. We detangle definitions: what is COVID-19 or SARS-CoV-2 or just plain old “coronavirus” and how are they different? What do we mean by a pandemic vs an endemic vs an epidemic?

If you loved what Ellie had to say you can find her on twitter (https://twitter.com/elliedemiology), and as always, you can follow Curiosity Killed the Rat on twitter (https://twitter.com/CuriosityRat), Insta (https://www.instagram.com/curiosityrat/), and facebook (https://www.facebook.com/curiosityrat/), and email in your listener questions to curiosityrat@gmail.com

Refences:

ACE-2 References:

https://www.sciencedirect.com/science/article/pii/S0092867420302294

https://www.nature.com/articles/ncomms4594

Reproductive number calculations:

https://www.nejm.org/doi/10.1056/NEJMoa2001316

Genome Sequencing and Origins

https://www.sciencedaily.com/releases/2020/03/200317175442.htm

https://www.ncbi.nlm.nih.gov/pubmed/16195424

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875465/

https://www.ncbi.nlm.nih.gov/pubmed/32007145

https://www.nature.com/articles/s41586-020-2012-7

Clinical features:

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30183-5/fulltext

COVID-19 vs. Flu

https://www.hopkinsmedicine.org/health/conditions-and-diseases/coronavirus/coronavirus-disease-2019-vs-the-flu

Kids and COVID-19

https://www.the-scientist.com/news-opinion/possible-biological-explanations-for-kids-escape-from-covid-19-67273

Respiratory droplets:

https://www.livescience.com/coronavirus-warm-weather-study.html

https://www.nejm.org/doi/10.1056/NEJMc2004973

SARS and MERS

https://virologyj.biomedcentral.com/articles/10.1186/s12985-015-0439-5

https://www.researchgate.net/publication/8953389_The_Severe_Acute_Respiratory_Syndrome

WHO Situation Reports:

https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports/

Others:

https://www.youtube.com/watch?v=iQsu3Kz9NYo (good visualisation of PCR)

https://www.technologynetworks.com/genomics/news/scientists-firmly-determine-that-sars-cov-2-was-not-engineered-332244?fbclid=IwAR1WIcJibcTaFw3C4aen5nzjihUO_jFVRIYOG7yHMii2MxRK98RZQDL6XLA

https://www.youtube.com/watch?v=7uP9bcNkvTM

https://www.youtube.com/watch?v=ddlRvqhGdPk

https://www.pharmacytimes.com/news/vitamin-d-helps-the-immune-system-during-cold-and-flu-season

https://www.ncbi.nlm.nih.gov/pubmed/30675873

https://www.washingtonpost.com/graphics/2020/world/corona-simulator/